Immunology

Serum Exchange Program

Serum Exchange Programs are determined on a year by year basis by a survey of enrolled Immunology Participants. These programs are dependant on donation of suitable samples by participants.

Frequency / Number of samples

/ Variable

Tests

EQA for rare disorder analytes with low participant numbers

Serum Free Light Chains

Serum or plasma – 500 μL provided for quantitation and qualitative asssessment of Serum Free Light Chains (kappa and lambda) and Serum Free Light Chain Ratio

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Serum Free Kappa Light Chains, Serum Free Lambda Light Chains and Serum Free Light Chain Ratio

Skin Antibodies

Serum 650 μL provided to determine the presence of Skin antibodies (Intercellular Substance, Basement Membrane)

Frequency / Number of samples

6 surveys / 1 sample per survey

Tests

Skin antibodies – Intercellular Substance antibodies (Pemphigus antibodies), Basement Membrane antibodies (Pemphigoid antibodies)

Specific Proteins

Serum – 900 μL provided for quantitation of Immunoglobulin G, Immunoglobulin A, Immunoglobulin M, Complement component 3, Complement component 4, α-1-antitrypsin, C1 esterase inhibitor, Haptoglobin, Caeruloplasmin, Prealbumin. Includes End of Cycle Performance Report.

Frequency / Number of samples

12 surveys / 2 samples per survey

Tests

Immunoglobulin G, Immunoglobulin A, Immunoglobulin M, Complement component 3, Complement component 4, α-1-antitrypsin, C1 esterase inhibitor, Haptoglobin, Caeruloplasmin, Prealbumin

Thyroid Antibodies

Serum – 500 μL provided for quantitation and qualitative assessment of Thyroid antibodies (Thyroglobulin antibodies, Thyroid Microsome antibodies, Thyroid Receptor antibodies)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Thyroglobulin antibodies, Thyroid microsome antibodies and Thyroid receptor antibodies.

Tissue Autoantibodies

Serum – 500 μL provided to determine the presence of Tissue Autoantibodies (Mitochondrial antibodies, Smooth Muscle antibodies, Liver Kidney Microsomal antibodies, F-actin antibodies, Parietal Cell antibodies, Intrinsic Factor antibodies)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Gastric Parietal Cell antibodies, Smooth Muscle antibodies, F-Actin antibodies, Mitochondrial antibodies, Liver/Kidney Microsome antibodies, Intrinsic Factor antibodies

Tryptase

Serum – 500 μL provided for quantitation of mast cell Tryptase

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Tryptase

Type I Diabetes Antibodies

Serum – 500 μL provided for quantitation and qualitative assessment of Type 1 Diabetes antibodies (Islet Cell antibodies, Glutamic Acid Decarboxylase antibodies, Islet Antigen-2 antibodies)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Islet cell antibodies, Glutamic Acid Decarboxylase antibodies, Insulinoma-associated-2 autoantibodies

Vasculitis Serology

Serum – 500 μL provided to determine the presence of Anti-Neutrophil Cytoplasmic antibodies (ANCA), Myeloperoxidase (MPO) antibodies, Proteinase 3 (PR3) antibodies and Anti-Glomerular Basement Membrane (GBM) antibodies

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Antineutrophil Cytoplasmic Antibodies, Myeloperoxidase Antibodies, Proteinase 3 Antibodies, Anti-glomerular basement membrane