Immunology

IgD

Serum – 500 μL provided for quantitation of serum Immunoglobulin D (IgD)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Immunoglobulin D

IgE (Total)

Serum – 500 μL provided for quantitation of serum Immunoglobulin E (IgE). Includes End of Cycle Performance Report.

Frequency / Number of samples

8 surveys / 2 samples per survey

Tests

Immunoglobulin E

IgG Subclasses

Serum – 500 μL provided for quantitation and qualitative assessment of IgG subclasses (IgG1, IgG2, IgG3, IgG4)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

IgG1, IgG2, IgG3, IgG4, Calculated subclass sum and IgG level obtained by total IgG assay

Immunophenotyping – Immunodeficiency

Lithium Heparin Whole Blood with commercial cell stabilizer – 1.5 mL. Provided to quantitate T and B Cell Lymphocyte Subsets (Percentages & Absolute Numbers)

Frequency / Number of samples

8 surveys / 2 samples per survey

Tests

T and B cell lymphocyte subsets. Lymphocytes of the following phenotypes (percentages): CD3 , CD3 CD4 , CD3 CD8 , CD19 , CD3-CD16 , CD3-CD56 , CD3-CD16 CD56 , Alpha-Beta and double positive or double negative lymphocytes. Lymphocytes of the following phenotypes (absolute numbers);CD3 , CD3 CD4 , CD3 CD8 , CD19

Inhalant Allergens

Serum – 1 mL provided for quantitation and qualitative assessment of Specific IgE to a range of Inhaled Allergens [Cat epithelium/dander, Rye grass pollen, Bermuda grass, Birch, House dust mite (Dermatophagoides pteronyssinus), Aspergillus fumigatus, Alternaria alternata/tenuis, Grass Pollen mix, Animal Epithelium mix, Mould mix]

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Specific IgE to Cat epithelium/dander, Rye grass pollen, Bermuda grass, Birch, House dust mite (Dermatophagoides pteronyssinus), Aspergillus fumigatus, Alternaria alternata/tenuis, Grass Pollen mix, Animal Epithelium mix, Mould mix

Myasthenia Gravis Antibodies

Serum or plasma- 400 μL provided for assessment of the presence of Acetylcholine Receptor antibodies and Skeletal Muscle antibodies

Frequency / Number of samples

4 surveys / 1 sample per survey

Tests

Acetylcholine Receptor Antibodies, Skeletal (Striated) Muscle Antibodies

Myositis Specific & Scleroderma Antibodies

Serum – 400 μL provided to determine the presence of Myositis Specific or Scleroderma antibodies

Frequency / Number of samples

6 surveys / 1 sample per survey

Tests

Myositis Specific & Scleroderma Antibodies – Cenp A, Cenp B, EJ, Fibrillarin, Jo-1, Ku, Mi-2, NOR-90, OJ, PDGFR, PL-7, PL-12, PM-Scl75, PMScl100, PR155, RNA Polymerase III, Ro-52, RPII, Scl70, Th/Th

Neuronal Antibodies

Serum – 500 μL provided to determine the presence of Neuronal antibodies (Paraneoplastic antibodies, NMDA Receptor antibodies, Neuromyelitis Optica (NMO, AQUP4) antibodies)

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Paraneoplastic Antibodies – Amphiphysin, CV2 (CRMP5), PNMA2 (Ma-2/Ta), Ri, Hu, Yo, Recoverin, SOX1, Titin, Zic 4, GAD, Tr (DNER), PCA-2, Neuromyelitis Optica (NMO, AQUP4) antibodies and Anti-NMDA Receptor antibodies.

Paraprotein

Serum – 500 μL, Urine – 20 mL provided to determine the presence (identification and quantitation) of paraproteins

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Paraprotein identification and concentration serum, Paraprotein identification and concentration urine

Procalcitonin

Lyophilised serum – 500 μL provided for quantitation (or semi-quantitation) of Procalcitonin

Frequency / Number of samples

8 surveys / 1 sample per survey

Tests

Procalcitonin

Rheumatic Disease Serology

Serum – 500 μL provided to determine the presence of Extractable Nuclear Antigen (ENA) antibodies, Anti-Double Stranded DNA (dsDNA) antibodies and Nucleosome antibodies

Frequency / Number of samples

8 surveys/1 sample each for ENA and dsDNA per survey

Tests

Extractable Nuclear Antigen Antibodies – SSA/Ro60, SS-B, PCNA. Jo-1, PM-Scl, Sm, Ribosomal P, Ro52, RNP, Scl-70, UPL , Anti-double stranded DNA Antibodies and Nucleosome Antibodies

Rheumatoid Factor

Serum – 500 μL provided for quantitation and qualitative assessment of Rheumatoid Factor. Includes End of Cycle Performance Report.

Frequency / Number of samples

8 surveys / 2 samples per survey

Tests

Rheumatoid Factor