Immunology

Participating laboratories may select from a group of RCPAQAP Immunology program modules that comprehensively cover the assays performed in Clinical Immunology.

Adrenal Antibodies

Material is supplied to determine the presence of Anti-adrenal antibodies.

Catalogue Number

17360102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, May, July, October

Measurand/Test

Anti-adrenal antibodies

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Anti-Saccharomyces Cerevisiae Antibodies

Material is supplied for the quantitation and qualitative assessment of Anti-Saccharomyces cerevisiae antibodies (IgG, IgA)

Catalogue Number

17030102

Frequency (No of surveys/year)

6

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, April, May, July, September, November

Measurand/Test

Anti-Saccharomyces cerevisiae IgA and IgG Antibodies (ASCA)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Antinuclear Antibodies

Material is supplied to determine the presence of Antinuclear antibodies including pattern, titre and appropriate commentary. 19 samples and 1 virtual sample are provided per year.

Catalogue Number

17010102

Frequency (No of surveys/year)

10

Cases/samples per survey

2

Sample Type

Serum

Sample volume

500uL

Schedule

February to November

Measurand/Test

Antinuclear antibodies pattern; Antinuclear antibodies titre (ANA)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Antiphospholipid Antibodies

Material is supplied for quantitation and qualitative assessment of Anticardiolipin and Anti-Beta 2-Glycoprotein 1 antibodies (IgG, IgA and IgM)

Catalogue Number

17020102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Cardiolipin IgG, IgA and IgM antibodies (aCL Abs), B2 Glycoprotein 1 IgG, IgA and IgM antibodies (b2GP1 Abs)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

B Cell Subsets

Material is supplied to quantitate B Cell Lymphocyte Subsets, specifically those related to Memory B Cell testing. The material assayed is fresh whole blood, which quickly deteriorates under normal transport conditions and should be tested within 48 hours of dispatch. As such this program is only available to a limited number of destinations outside Australia, New Zealand and Malaysia. Please contact Customer Service Team if you are outside these areas.

Catalogue Number

17390102

Frequency (No of surveys/year)

2

Cases/samples per survey

2

Sample Type

EDTA whole blood

Sample volume

1.3 mL

Schedule

May, September

Measurand/Test

B Cells of the following subtypes (percentage of PBLs and B Cells): memory B cells, naïve B Cells, marginal zone B Cells, transitional B Cells, switched memory B cells, CD21low cells.

Storage and Handling

Samples must be tested within 24 hours of receipt. Store at room temperature (18-24°C ) until processing.

Product details last updated on May 22, 2023

Bee Venom IgE

Material supplied for the quantitation and qualitative assessment of Specific IgE to Bee Venom

Catalogue Number

17040102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Specific IgE to Bee Venom (Apis mellifera)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Coeliac Disease Antibodies

Material is supplied for quantitation and qualitative assessment of Coeliac disease antibodies.

Catalogue Number

17060102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Deamidated Gliadin IgG and IgA (DGP); Tissue transglutaminase IgG and IgA (tTG); Endomysial antibodies (EMA)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Cyclic Citrullinated Peptide

Material is supplied for quantitation and qualitative assessment of Cyclic citrullinated peptide antibody

Catalogue Number

17070102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Cyclic citrullinated peptide antibody (CCP)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Drug Allergens

Material is supplied for quantitation and qualitative assessment of Specific IgE to a range of Drug Allergens

Catalogue Number

17080102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, May, July, October

Measurand/Test

Specific IgE to Drugs (Latex, Morphine, Chlorhexidine, Penicilloyl V, Penicilloyl G, Cefaclor, Suxamethonium (Succinylcholine), Ampicilloyl, Amoxicilloyl)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

dsDNA and Associated Antibodies

Material is supplied to determine the presence of dsDNA and associated antibodies (nucleosome and histone).

Catalogue Number

17370102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

dsDNA, nucleosome, histone.

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Extractable Nuclear Antigen (ENA) Antibodies

Material is supplied to determine the presence of Extractable Nuclear Antigen (ENA) antibodies

Catalogue Number

17380102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Extractable Nuclear Antigen (ENA) antibodies: SS-A (Ro60), SS-B, PCNA, Centromere, Jo-1, Pm-Scl, Sm, Ribosomal P, Ro52, RNP, Scl-70,DFS-70.

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Food Allergens

Material is supplied for quantitation and qualitative assessment of Specific IgE to a range of Food Allergens

Catalogue Number

17090102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Specific IgE to Food Allergens (Prawn, peanut, cashew, cow’s milk, egg, sesame seed, soy, wheat grain, Omega-5 gliadin, Ovomucoid, Ara-h2)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Fungal and Avian Antibodies

Material is supplied for the quantitation and qualitative assessment of Fungal and Avian antibodies.

Catalogue Number

17380202

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, May, July, October

Measurand/Test

IgG antibodies to Aspergillus fumigatus; IgG antibodies to Budgie; IgG antibodies to Pigeon

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

High Sensitivity C Reactive Protein (hsCRP)

Material is supplied for quantitation of high sensitivity CRP (<20mg/L)

Catalogue Number

17120102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Liquid sample

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

High sensitivity CRP (<20mg/L) (hsCRP)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on September 1, 2023

HLA B27 Status

Material is supplied to determine the presence of Human Leukocyte Antigen B27. The material assayed is fresh whole blood, which quickly deteriorates under normal transport conditions and should be tested within 48 hours of dispatch. As such this program is only available to a limited number of destinations outside Australia, New Zealand and Malaysia. Please contact Customer Service Team if you are outside these areas.

Catalogue Number

17130102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

EDTA whole blood

Sample volume

1mL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Human Leukocyte Antigen B27 (HLA B27)

Storage and Handling

Samples must be tested within 24 hours of receipt. Store at room temperature (18-24°C) until processing.

Additional Comments

The material assayed is fresh whole blood, which quickly deteriorates under normal transport conditions and should be tested within 48 hours of dispatch. As such this program is only available to a limited number of destinations outside Australia, New Zealand and Malaysia. Please contact Customer Service at [email protected] if you are outside these areas.


Product details last updated on May 22, 2023

Immunoglobulin D

Material is supplied for quantitation of serum Immunoglobulin D (IgD)

Catalogue Number

17150102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, May, July, October

Measurand/Test

Immunoglobulin D (IgD)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Immunoglobulin E

Material is supplied for quantitation of serum Immunoglobulin E (IgE)

Catalogue Number

17160102

Frequency (No of surveys/year)

6

Cases/samples per survey

2

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, July, August, October

Measurand/Test

Immunoglobulin E (IgE)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Immunoglobulin G Subclasses

Material is provided for quantitation and qualitative assessment of IgG subclasses

Catalogue Number

17140102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

IgG1, IgG2, IgG3, IgG4, Calculated subclass sum and IgG level obtained by total IgG assay

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Immunology Case Study

This program offers Immunology clinical case studies. This is a paperwork only program and no samples are provided. Five clinical cases are provided per year and the program is available to all staff from an enrolled Participant site.

Catalogue Number

17050302

Frequency (No of surveys/year)

5

Cases/samples per survey

1

Sample Type

No sample

Schedule

February, April, June, August, October

Product details last updated on October 4, 2024

Immunophenotyping

Material is supplied to quantitate T and B Cell Lymphocyte Subsets (Percentages and Absolute Numbers). The material assayed is fresh whole blood, which quickly deteriorates under normal transport conditions and should be tested within 3–4 days of dispatch. As such this program is only available to a limited number of destinations outside Australia, New Zealand, Malaysia, Singapore and Hong Kong. Please contact the Customer Service Team if you are outside these areas.

Catalogue Number

17170102

Frequency (No of surveys/year)

8

Cases/samples per survey

2

Sample Type

EDTA whole blood with commercial cell stabiliser

Sample volume

1.2mL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Lymphocytes of the following phenotypes (percentages): CD3+, CD3+CD4+, CD3+CD8+, CD19+, CD3-CD16+, CD3-CD56+, CD3-CD16+CD56+, Alpha-Beta|Double negative or double positive lymphocyte percentages|Lymphocytes of the following phenotypes (absolute numbers); CD3+, CD3+CD4+, CD3+CD8+, CD19+

Storage and Handling

Samples must be tested within 24 hours of receipt. Store at room temperature (18-24°C) until processing.

Additional Comments

The material assayed is fresh whole blood, which quickly deteriorates under normal transport conditions and should be tested within 3–4 days of dispatch. As such this program is only available to a limited number of destinations outside Australia, New Zealand, Malaysia, Singapore and Hong Kong. Please contact Customer Service at [email protected] if you are outside these areas.


Product details last updated on May 22, 2023

Inhalant Allergens

Material is supplied for quantitation and qualitative assessment of Specific IgE to a range of Inhalant Allergens

Catalogue Number

17180102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

1mL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Specific IgE to Cat epithelium/dander, Rye grass pollen, Bermuda grass, House dust mite (Dermatophagoides pteronyssinus), Aspergillus fumigatus, Alternaria alternata/tenuis, Grass Pollen mix, Animal Epithelium mix, Mould mix, Birch

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Liver Antibodies

Material is supplied to determine the presence of Liver Specific Antibodies.

Catalogue Number

17190102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, May, July, October

Measurand/Test

Liver specific autoantibodies: AMA-M2, M2-3E, LKM-1, LC-1, SLA/LP, Sp100, gp210, PML, Ro-52

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Myasthenia Gravis Antibodies

Material is supplied for assessment of the presence of Acetylcholine Receptor antibodies and Skeletal Muscle antibodies

Catalogue Number

17210102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Serum/Plasma

Sample volume

400uL

Schedule

February, May, July, October

Measurand/Test

Acetylcholine Receptor Antibodies (AChR); Skeletal (Striated) Muscle Antibodies (Anti-Str)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Myositis Specific and Scleroderma Antibodies

Material is supplied to determine the presence of Myositis specific or Scleroderma antibodies

Catalogue Number

17220102

Frequency (No of surveys/year)

6

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, April, May, July, September, November

Measurand/Test

Myositis and scleroderma antibodies: Mi-2, Mi-2α, MI-2β, Ku, RNA Pol III, Cenp A, Cenp B, MDA5, NXP2, SAE, TIF1γ, PL-7, PL-12, OJ, EJ, Jo-1, PM-Scl75, PM-Scl100, SRP, Ro52, Scl-70, Fibrillarin, NOR-90, Th/To, PDGFR, cN-1A, HMGCR, others as appropriate

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on November 28, 2024

Neuronal Antibodies

Material is supplied to determine the presence of Neuronal antibodies

Catalogue Number

17230102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Antibodies to Paraneoplastic Antigens (Hu, Yo, Ri, CV2, PNMA2 (Ma2/Ta), Amphiphysin, Recoverin, SOX1, Titin, Zic4, GAD65, Tr (DNER)); Anti-NMDA Receptor Antibodies (NMDA-R,); Neuromyelitis Optica Antibodies (NMO/AQP4)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Paraproteins

Material is supplied to measure and report electrophoresis fractions and determine the presence (identification and quantitation) of paraproteins

Catalogue Number

17240102

Frequency (No of surveys/year)

8

Cases/samples per survey

2

Sample Type

Serum and Urine

Sample volume

500uL and 20mL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Serum electrophoresis fractions (albumin, alpha-1, alpha-2, beta, beta-1, beta-2, gamma, residual gamma); Paraprotein identification and concentration (urine)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Procalcitonin

Material is supplied for quantitation (or semi-quantitation) of Procalcitonin

Catalogue Number

17250102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Lyophilised serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Procalcitonin (PCT)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on May 22, 2023

Rheumatoid Factor

Material is supplied for quantitation and qualitative assessment of Rheumatoid Factor.

Catalogue Number

17270102

Frequency (No of surveys/year)

6

Cases/samples per survey

2

Sample Type

Serum

Sample volume

500uL

Schedule

February, March, May, July, August, October

Measurand/Test

Rheumatoid Factor (RF)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on May 22, 2023

Serum Free Light Chains

Material is supplied for quantitation and qualitative assessment of Serum Free Light Chains and Serum Free Light Chain Ratio

Catalogue Number

17280102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Lyophilised serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Serum free kappa light chains (FKLC); Serum free lambda light chains (FLLC); Serum free light chain ratio (K:L Ratio)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on March 12, 2024

Skin Antibodies

Material is supplied to determine the presence of Skin antibodies

Catalogue Number

17290102

Frequency (No of surveys/year)

6

Cases/samples per survey

1

Sample Type

Serum

Sample volume

650uL

Schedule

February, April, May, July, September, November

Measurand/Test

Skin Intercellular Substance antibodies (ICS), Skin Basement Membrane antibodies (BMZ), Desmoglein 1, Desmoglein 3, BP180, BP230.

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Specific Proteins

Material is supplied for quantitation of Specific Proteins

Catalogue Number

17300102

Frequency (No of surveys/year)

10

Cases/samples per survey

2

Sample Type

Serum

Sample volume

1mL

Schedule

February, March, April, May, June, July, August, September, October, November

Measurand/Test

Immunoglobulin G (IgG), Immunoglobulin A (IgA), Immunoglobulin M (IgM), Complement component 3 (C3), Complement component 4 (C4), α-1-antitrypsin (A1AT, AAT), C1 esterase inhibitor (C1-inh), Haptoglobin (Hapt), Caeruloplasmin, Prealbumin (Transthyretin)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on May 22, 2023

Thyroid antibodies

Material is supplied for quantitation and qualitative assessment of Thyroid antibodies

Catalogue Number

17310102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Thyroglobulin antibodies (TgAb), Thyroid microsome antibodies (TPO), Thyroid receptor antibodies (TRAb), Thyroid Stimulating Immunoglobulin

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Tissue Autoantibodies

Material is supplied to determine the presence of Tissue Autoantibodies

Catalogue Number

17320102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Gastric Parietal Cell antibodies (APC), Smooth Muscle antibodies (SMA), F-Actin antibodies (F-actin), Mitochondrial antibodies (AMA), Liver/Kidney Microsome antibodies (LKM), Intrinsic Factor antibodies (Blocking antibody) (IF)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Tryptase

Material is supplied for quantitation of mast cell Tryptase

Catalogue Number

17330102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Lyophilised serum

Sample volume

500uL

Schedule

February, March, May, June, July, August, September, November

Measurand/Test

Mast Cell Tryptase (Trypt)

Storage and Handling

Upon receipt, store samples at 2-8°C

Product details last updated on May 22, 2023

Type I Diabetes Antibodies

Material is supplied for quantitation and qualitative assessment of Type 1 Diabetes antibodies

Catalogue Number

17340102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Islet cell antibodies (ICA); Glutamic Acid Decarboxylase antibodies (GAD); Insulinoma-associated-2 autoantibodies (IA2 antibodies), Znt8

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023

Vasculitis Antibodies

Material is supplied to determine the presence of Anti-Neutrophil Cytoplasmic antibodies (ANCA), Myeloperoxidase (MPO) antibodies, Proteinase 3 (PR3) antibodies and Anti-Glomerular Basement Membrane (GBM) antibodies

Catalogue Number

17350102

Frequency (No of surveys/year)

8

Cases/samples per survey

1

Sample Type

Serum

Sample volume

500uL

Schedule

Monthly: February to May and July to October

Measurand/Test

Anti-neutrophil Cytoplasmic Antibodies (ANCA), Myeloperoxidase Antibodies (MPO-ANCA), Proteinase 3 Antibodies (PR3-ANCA), Anti-glomerular basement membrane (GBM)

Storage and Handling

Upon receipt, store samples at -20°C

Product details last updated on May 22, 2023