Haematology

Haematology is the discipline of pathology which deals with diseases which affect the blood such as anaemia, leukemia, lymphoma, and clotting or bleeding disorders. The RCPAQAP Haematology EQA programs cover a wide range of tests used in laboratory haematology.

Additional Factors – Module 1

Lyophilised plasma – 1 mL provided to assess Factor VIII / IX measurements

Frequency / Number of samples

6 surveys / 2 samples per survey

Tests

Factor VIII, Factor IX

Additional Factors – Module 2

Lyophilised plasma – 1 mL provided to assess Factor II/ V / VII / X / XI / XII measurements

Frequency / Number of samples

3 surveys / 2 samples per survey

Tests

Factor II, Factor V, Factor VII, Factor X, Factor XI, Factor XII

Automated Differential

Stabilised whole blood – 2.5 mL to 3 mL provided to assess the white cell differential from 3-part of 5-part differential from automated intstruments.

Frequency / Number of samples

4 surveys / 2 samples per survey

Tests

Instrument specific material for automated differential counts

Bone Marrow Morphology

Virtual images of peripheral blood and bone marrow / trephine provided to assess the capabilities of describing and diagnosing bone marrow morphology.

Frequency / Number of samples

2 surveys / 1 cases per survey

Tests

Description & Diagnostic Interpretation of peripheral blood films, Bone Marrow aspirate and Trephine sections

CD34+

Stabilised whole blood – ~0.6 mL provided to assess CD34+

Frequency / Number of samples

3 surveys / 2 samples per survey

Tests

WCC, %, Total CD34/uL

D-Dimer – Module 1

Stabilised Liquid – 1 mL provided to assess D-Dimer on automated techniques

Frequency / Number of samples

4 surveys / 2 samples per survey

Tests

D-Dimer – fully quantitative

D-Dimer – Module 2

Lyophilised plasma – 0.5 mL provided to assess D-Dimer on semi quantitative / qualitative methods.

Frequency / Number of samples

4 surveys / 2 samples per survey

Tests

D-Dimer – semi quantitative / qualitative

ESR – Module 1 & 2

Stabilised whole blood – 2 to 5 mL provided to assess ESR

Frequency / Number of samples

4 surveys / 2 samples per survey

Tests

Method specific material for ESR testing

Full Blood Count

Stabilised whole blood – 1.5 mL provided to assess Full Blood Count parameters.

Frequency / Number of samples

12 surveys / 2 samples per survey

Tests

White Blood Cells, Red Blood Cells, Haemoglobin, Haematocrit, Mean Cell Volume, Mean Cell Haemoglobin, Mean Cell Haemoglobin Concentration, Red Cell Distribution Width – CV, Platelet, Mean Platelet Volume

G6PD

Lyophilised haemolysate – 0.5 mL provided to assess the G6PD screen and assay

Frequency / Number of samples

2 surveys / 2 samples per survey

Tests

Glucose-6-phosphate dehydrogenase Screen, Glucose-6-phosphate dehydrogenase Assay

Haematology Immunophenotyping – Module 1

Stabilised PB/BM cells – 0.8 to 1.5 mL provided to assess the Immunophenotype of patient case studies

Frequency / Number of samples

4 surveys / 1 samples per survey

Tests

Haematology Immunophenotyping (AML, T and B cell ALL and LPD-Diagnostic Interpretation)

Haematology Immunophenotyping – Module 2

Stabilised PB/BM cells – 1.0 mL provided to assess the detection of the PNH clone in red cell, granulocyte and monocyte markers.

Frequency / Number of samples

2 surveys / 2 samples per survey

Tests

PNH Testing