Chemical Pathology

CSF Oligoclonal Bands

Lyophilised CSF and Lyophilised Matching Serum – 0.5mL vials to assess and interpret oligoclonal bands and Beta-2 Transferrin in CSF

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Oligoclonal Banding (CSF), Oligoclonal Banding (serum), Beta-Trace Protein, Beta-2 Transferrin, Interpretive Comment

Dried Blood Spot

Whole blood (dried) – 2 x75uL cards to assess inborn errors of metabolism

Frequency / Number of samples

6 surveys per year / 3 samples per survey

Tests

17-Hydroxy-Progesterone (17-OHP)

Phenylalanine

Immunoreactive trypsinogen (IRT)

TSH

Tyrosine

Clinical Evaluation Component

Endocrine

Lyophilised Serum – 5mL vials to assess performance for a range of endocrine assays

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

α Fetoprotein, CA-125, CEA, Ferritin, Folate, FSH, Growth Hormone, Homocysteine, hCG (Total), Insulin, LH, Prolactin, PTH, SHBG, TSH, Free T3, Free T4, Vitamin B12

Endocrine: Angiotensin-converting Enzyme

Lyophilised Serum – 0.25mL vials to assess Angiotensin Converting Enzyme assay performance

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Angiotensin Converting Enzyme (ACE)

Endocrine: Anti-Mullerian Hormone

Lyophilised Serum – 2mL vials to assess Anti-Mullerian Hormone

Frequenct / Number of samples

12 surveys per year / 2 samples per survey

Tests

Anti-Mullerian Hormone

Endocrine: Parathyroid Hormone (PTH)

Lyophilised Serum – 0.5mL vials to assess PTH measurements

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Parathyroid Hormone

Renin

Endocrine: Prostate Specific Antigen (PSA)

Lyophilised Serum – 3mL vials to assess PSA measurements

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Total PSA, Free PSA

Endocrine: Red Cell Folate

Lyophilised Whole Blood – 1mL vials to assess Red Cell Folate measurements

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Red Cell Folate

Endocrine: Special

Lyophilised Serum – 5mL vials to assess performance for a range of endocrine assays

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Aldosterone, Androstenedione, Cortisol, DHEA Sulphate, 17 Hydroxyprogesterone, Oestradiol, Oestriol (unconjugated), Progesteron, Testosterone, Total T3, Total T4, Vitamin D3 (25 Hydroxy Vitamin D), P1NP, Dihydrotestosterone, Active B12 (Holotranscobalamin), serum-Beta CTX, 11-Deoxycortisol

Faecal Occult Blood

Lyophilised Human Blood – 1mL vials to assess occult blood levels against assay cutoff.

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Faecal Occult Blood (Quantitative), Faecal Occult Blood (Qualitative)

General Serum Chemistry

Lyophilised Serum and  Matching Diluent – 5mL vials to assess performance across a range of routine chemical pathology assays including therapeutic drugs and endocrine.

Frequency / Number of samples

24 surveys per year / 2 samples per survey

Tests

Albumin, Bicarbonate, Bilirubin-Total, Bilirubin-Conjugated, Icterus (Quantitative, Icterus (Qualitative), Calcium, Chloride, Creatinine, Fructosamine, Glucose, Lactate, Lithium, Magnesium, Osmolality, Phosphate (Inorganic), Potassium, Protein (Total), Sodium, Urate, Urea, Troponin I (quantitative), Troponin T (quantitative), Troponin T (semi-qualitative) Roche Cardiac Reader only, Troponin T (qualitative)

Enzymes: ALT, Alkaline Phosphatase, Amylase, AST, Cholinesterase, Creatine Kinase, CK-MB, GGT, Lactate Dehydrogenase, Lipase, Iron, TIBC, Transferrin, Ferritin

Lipids: Cholesterol, HDL Cholesterol, Triglyceride

Endocrine: Cortisol, Thyroxine, Free T4, TSH, Total T3, Free T3, hCG (quantitative), hCG (qualitative)

Drugs: Carbamazepine, Digoxin, Paracetamol, Phenobarbitone, Phenytoin, Salicylate, Theophylline, Valproate, Gentamicin, Vancomycin

Note. Troponin T (semi-qualitative) on Roche Instruments. Participants using the Roche Cardiac Reader should enrol in the General Serum Chemistry Program. Participants using Roche cobas h232 instruments should enrol in the PoCT Troponin Program. This is due to the different cut-offs, standardisation and units of these 2 instruments.

General Urine Chemistry

Lyophilised Urine – 10mL vials to assess performance across a range of chemistry urine assays

Frequency / Number of samples

12 surveys per year / 2 samples per survey

Tests

Albumin

ACR

Calcium

Chloride

Cortisol

Creatinine

Free Deoxypyridinoline

Free Metanephrine

Free Normetanephrine

Free 3-Methoxytyramine

Glucose

hCG-Qualitative

hCG-Quantitative

Magnesium

N-Telopeptides

Osmolality

Phosphate

Potassium

Sodium

Total Protein

Urate

Urea