Anatomical Pathology Archives - RCPAQAP : RCPAQAP

ALK Translocation for non-small cell lung carcinoma (NSCLC): FISH

Provide annual technical proficiency testing for laboratories staining FFPE tissue with ALK Fluorescent in situ Hybridisation (FISH). Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13010102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK FISH

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

ALK Translocation for non-small cell lung carcinoma (NSCLC): IHC

Provide annual technical proficiency testing for laboratories staining FFPE tissue with ALK immunohistochemistry (IHC). Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13020102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK IHC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

ALK Translocation for non-small cell lung carcinoma (NSCLC): Molecular

Provide annual technical proficiency testing for laboratories processing FFPE tissue for ALK translocation using molecular techniques. Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13030102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK Molecular

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Breast Diagnostic

Provide annual diagnostic learning and proficiency testing in breast surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13040102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Breast Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of breast pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Dermatopathology Diagnostic

Provide annual diagnostic learning and proficiency testing in dermatopathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13050102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Skin Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of dermatopathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Electron Microscopy Diagnostic

Provide annual diagnostic learning and proficiency testing in transmission electron microscopy to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include two medical renal biopsy cases.

Catalogue Number

13060102

Frequency (No of surveys/year)

1

Cases/samples per survey

Three diagnostic challenges (including two renal biopsies) are provided as transmission electron micrographs, and light microscopy if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

September

Measurand/Test

Transmission Electron Microscopy

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of transmission electron microscopy interpretation and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Electron Microscopy Technical

Provide annual proficiency testing for laboratories processing transmission electron microscopy specimens.

Catalogue Number

13070102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Submission of Electron Micrographs prepared by the laboratory. Laboratory practice questionnaire.

Schedule

September

Measurand/Test

Transmission Electron Microscopy techniques

Product details last updated on August 20, 2025

Fluorescence in-situ Hybridisation (FISH) Diagnostic

Provide annual proficiency testing for laboratories reporting solid tumour fluorescence in-situ hybridisation. A different probe is tested each year.

Catalogue Number

13310102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections to be stained and interpreted for ETV6 rearrangement in 2026.

Schedule

April

Measurand/Test

ETV6

Product details last updated on August 20, 2025

Forensic Diagnostic

Provide annual diagnostic learning and proficiency testing in forensic pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include histopathology and medical imaging for interpretation.

Catalogue Number

13080102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Forensic Pathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of forensic pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Gastrointestinal Diagnostic

Provide annual diagnostic learning and proficiency testing in gastrointestinal surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13090102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Gastrointestinal Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of gastrointestinal pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

General Diagnostic

Provide ongoing diagnostic learning and proficiency testing in general surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities, across various organ systems.

Catalogue Number

13100102

Frequency (No of surveys/year)

3

Cases/samples per survey

10

Sample Type

Thirty diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

February, May, September

Measurand/Test

General Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of general surgical pathology and will be able to identify gaps in their diagnostic skills.

The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Gynaecology Diagnostic

Provide annual diagnostic learning and proficiency testing in gynaecological surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13110102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Gynaecological Pathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of gynaecological pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

HER2 Brightfield ISH (BRISH) Breast Diagnostic

Provide annual proficiency testing in HER2 ISH analysis to individual pathologists reporting breast cases. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of amplified and non amplified invasive breast cancers.

Catalogue Number

13320101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Dual probe HER2 BRISH for breast cancer interpretation.

Additional Comments

Learning objective: Upon completion of this activity, participants will be able to identify gaps in their interpretation of brightfield in situ hybridisation staining in breast cases.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

HER2 Brightfield ISH (BRISH) Breast Technical

Provide annual proficiency testing for laboratories performing HER2 brightfield in situ hybridisation for breast cases.

Catalogue Number

13250102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Breast

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

HER2 Brightfield ISH (BRISH) Gastric Diagnostic

Provide annual proficiency testing in HER2 ISH analysis to individual pathologists. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of amplified and non amplified invasive gastric cancers.

Catalogue Number

13130101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

HER2 BRISH for gastric cancer interpretation

Additional Comments

Learning objective: Upon completion of this activity, participants will be able to identify gaps in their interpretation of brightfield in situ hybridisation staining in gastric cases.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

HER2 Brightfield ISH (BRISH) Gastric Technical

Provide annual proficiency testing for laboratories performing HER2 brightfield in situ hybridisation for gastric cases.

Catalogue Number

13260102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Gastric

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

HPV BRISH Technical

Provide proficiency testing for laboratories performing HPV brightfield in situ hybridisation in head and neck cases.

What's new

New for 2026

Catalogue Number

13600102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HPV BRISH

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 22, 2025

Immunohistochemistry Breast Markers

Provide annual proficiency testing for laboratories processing immunohistochemistry. The staining of a variety of breast markers is assessed.

Catalogue Number

13150102

Frequency (No of surveys/year)

1

Cases/samples per survey

5

Sample Type

Unstained formalin fixed paraffin sections comprising of 5 breast cancer cases in a composite tissue block to be stained for ER, PR, HER2 and 2 additional antibodies.

Schedule

May

Measurand/Test

ER, PR, HER2 IHC, CD34, S100

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

PD-L1 for TNBC interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.

Product details last updated on August 20, 2025

Immunohistochemistry Breast Markers Audit

Quality assurance activity for laboratories reporting immunohistochemistry (IHC) and in-situ hybridization (ISH) breast markers through an audit of clinical results. There is no technical component to this survey, but it comprises online submission of the hormone receptor and HER2 status for each case of early invasive primary (not stage 4 disease) breast carcinoma. 50-100 samples are required for assessment. Laboratories providing less than 50 samples will not qualify for assessment.

Catalogue Number

13160102

Frequency (No of surveys/year)

1

Cases/samples per survey

100

Sample Type

A maximum of 100 cases from the preceding year are submitted.

Schedule

February

Measurand/Test

Breast marker audit of cases reported by participant

Product details last updated on August 3, 2021

Immunohistochemistry General

Provide annual proficiency testing for laboratories processing immunohistochemistry. The staining of a variety of markers across various organ systems is assessed.

Catalogue Number

13170102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 general markers

Schedule

February

Measurand/Test

Calretinin (MTAP); PTEN (NKX3.1); p16 (AE1/AE3)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry HER2-low scoring in Breast Cancer

Provide annual proficiency testing to individual pathologists, trainees and laboratories applying an HER2 IHC score. Participants can assess their scoring skills and compare performance with that of their peers and selected scoring experts, with the purpose of performance improvement.

Catalogue Number

13550101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Six challenges are provided as whole slide H&E and HER2 IHC images in the myQAP portal. USBs cannot be purchased for this program.

Schedule

July

Measurand/Test

HER2 IHC readout

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of the scoring of HER2 IHC low-level expression and can apply these learnings to ensure appropriate treatment in unresectable or metastatic breast cancer.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 25, 2025

Immunohistochemistry Lymphoma Markers

Provide annual proficiency testing for laboratories processing immunohistochemistry. The staining of a variety of lymphoma markers is assessed.

Catalogue Number

13180102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 lymphoma markers.

Schedule

February

Measurand/Test

TdT (CD7); IgG4 (CD79a); CD19 (c-Myc)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry Mismatch Repair (MMR) protein

Provide annual proficiency testing for laboratories processing immunohistochemistry. Two mismatch repair (MMR) proteins are assessed annually. Colorectal cases are assessed annually and non-colorectal cases are rotated annually.

Catalogue Number

13430102

Frequency (No of surveys/year)

1

Cases/samples per survey

4

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 2 MMR protein markers.

Schedule

August

Measurand/Test

MLH1 and PMS2 on colorectal carcinoma and a second tissue type

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry PD-L1 for HNSCC

Provide PD-L1 expression predictive biomarker staining/technical proficiency testing to laboratories performing PD-L1 staining in HNSCC for pembrolizumab (Keytruda). The purpose of this program is to assess the laboratory’s ability to specifically detect PD-L1 expression when compared with the commercial assay reference.

Catalogue Number

13460102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for HNSCC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry PD-L1 for NSCLC

Provide PD-L1 expression predictive biomarker staining/technical proficiency testing to laboratories performing PD-L1 staining in NSCLC for pembrolizumab (Keytruda). The purpose of this program is to assess the laboratory’s ability to specifically detect PD-L1 expression when compared with the commercial assay reference.

For pathologist scoring proficiency testing, please see the program “Immunohistochemistry PD-L1 scoring in NSCLC (TPS)”

Catalogue Number

13440102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for NSCLC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry PD-L1 for TNBC

Provide PD-L1 expression predictive biomarker staining/technical proficiency testing to laboratories performing PD-L1 staining in TNBC for pembrolizumab (Keytruda). The purpose of this program is to assess the laboratory’s ability to specifically detect PD-L1 expression when compared with the commercial assay reference.

For pathologist scoring proficiency testing, please see the new program “Immunohistochemistry PD-L1 scoring in TNBC (CPS)”

Catalogue Number

13450102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for TNBC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Immunohistochemistry PD-L1 scoring in NSCLC (TPS)

Provide PD-L1 expression predictive biomarker scoring proficiency testing to individual pathologists, trainees and laboratories applying a Tumour Proportion Score (TPS) in NSCLC for pembrolizumab (Keytruda). Participants can assess their scoring skills and compare performance with that of their peers and selected scoring experts, with the purpose of performance improvement.

For laboratory technical proficiency testing, please refer to program “Immunohistochemistry PD-L1 for NSCLC”.

Catalogue Number

13560101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Six Tumour Proportion Score challenges are provided as whole slide H&E and PD-L1 images in the myQAP portal. USBs cannot be purchased for this program.

Schedule

August

Measurand/Test

PD-L1 in NSCLC TPS readout

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of the scoring of PD-L1 IHC expression in non small cell lung cancer and can apply these learnings to ensure appropriate treatment where a companion diagnostic test is required.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 25, 2025

Immunohistochemistry PD-L1 scoring in TNBC (CPS)

Provide PD-L1 expression predictive biomarker scoring proficiency testing to individual pathologists, trainees and laboratories applying a Combined Proportion Score (CPS) in TNBC for pembrolizumab (Keytruda). Participants can assess their scoring skills and compare performance with that of their peers and selected scoring experts, with the purpose of performance improvement.
For laboratory technical proficiency testing, please refer to program “Immunohistochemistry PD-L1 for TNBC”.

What's new

New for 2026

Catalogue Number

13590102

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Six Combined Proportion Score challenges are provided as whole slide H&E and PD-L1 images in the myQAP portal. USBs cannot be purchased for this program.

Schedule

August

Measurand/Test

PD-L1 in TNBC CPS readout

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of the scoring of PD-L1 IHC expression in triple negative breast cancer and can apply these learnings to ensure appropriate treatment where a companion diagnostic test is required.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Melanocytic Lesions Diagnostic

Provide diagnostic learning and proficiency testing in surgically resected melanocytic lesions to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

What's new

New for 2026

Catalogue Number

13580102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Melanocytic Lesions Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of melanocytic lesions pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Mohs Diagnostic

Provide ongoing diagnostic learning and proficiency testing in Mohs surgery pathology to individual dermatologists and trainees. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement.

Catalogue Number

13190102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images in the myQAP portal.

Schedule

March

Measurand/Test

Mohs surgery histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of skin pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Neuropathology Diagnostic

Provide ongoing diagnostic learning and proficiency testing in neuropathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13200102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Neuropathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of neuropathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Neuropathology Immunohistochemistry and Technical

Provide annual proficiency testing for laboratories processing immunohistochemistry and special stains on neuropathology specimens. The staining of specific markers for neural tissue is assessed.

Catalogue Number

13140102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

This is a combined module where unstained formalin fixed paraffin sections are provided for immunohistochemical and special staining.

Schedule

May

Measurand/Test

p53 and AFB stain

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Oral and Maxillofacial Diagnostic

Provide ongoing diagnostic learning and proficiency testing in oral surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13210102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Oral and Maxillofacial Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of oral and maxillofacial pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Paediatric Diagnostic

Provide ongoing diagnostic learning and proficiency testing in paediatric and peri-natal pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13220102

Frequency (No of surveys/year)

1

Cases/samples per survey

12

Sample Type

Twelve diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Paediatric Histopathology, Perinatal Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of paediatric and peri-natal pathology and will be able to identify gaps in their diagnostic skills.

The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): FISH

Provide annual technical proficiency testing for laboratories staining FFPE tissue with ROS1 Fluorescent in situ Hybridisation (FISH). Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13360102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 FISH

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.

Product details last updated on August 20, 2025

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): IHC

Provide annual technical proficiency testing for laboratories staining FFPE tissue with ROS1 immunohistochemistry (IHC). Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13370102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 IHC

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.

Product details last updated on August 20, 2025

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): Molecular

Provide annual technical proficiency testing for laboratories processing FFPE tissue for ROS1 translocation using molecular techniques. Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13380102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 Molecular

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.

Product details last updated on August 20, 2025

Sarcoma Gene Testing – FISH

Provide annual diagnostic proficiency testing for laboratories staining and reporting sarcoma gene testing from FFPE tissue with Fluorescent in situ Hybridisation (FISH). Two genes are assessed annually.

Catalogue Number

13480102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

MDM2 and COL1A1-PDGFB fusion in 2026

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Sarcoma Gene Testing – IHC

Provide annual diagnostic proficiency testing for laboratories staining and reporting sarcoma gene testing from FFPE tissue with immunohistochemistry (IHC). Two genes are assessed annually.

Catalogue Number

13500102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

MDM2 and COL1A1-PDGFB fusion in 2026

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Sarcoma Gene Testing – Molecular

Provide annual diagnostic proficiency testing for laboratories processing and reporting sarcoma gene testing from FFPE tissue with molecular techniques. Two genes are assessed annually.

Catalogue Number

13510102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

MDM2 and COL1A1-PDGFB fusion in 2026

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Technical Frozen Section

Provide annual proficiency testing for histopathology laboratories performing the frozen section procedure.

Catalogue Number

13230102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Participants submit a stained and coverslipped section on a glass slide for assessment of block/section preparation and staining.

Schedule

February

Measurand/Test

Frozen section

Product details last updated on August 20, 2025

Technical General

Provide ongoing proficiency testing for laboratories performing general histotechniques such as special stains, haematoxylin and eosin staining, processing and sectioning.

Catalogue Number

13240102

Frequency (No of surveys/year)

2

Cases/samples per survey

1-2

Sample Type

Unstained formalin fixed paraffin sections are provided for most exercises. Unstained tissue sections are submitted by participants for the Processing and Sectioning exercise

Schedule

February, August

Measurand/Test

H&E, Processing and Sectioning, Gram special stain and Elastin special stain

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 20, 2025

Thoracic Diagnostic

Provide diagnostic learning and proficiency testing in thoracic surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13490102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Thoracic Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of thoracic pathology and will be able to identify gaps in their diagnostic skills.
The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025

Urology Diagnostic

Provide ongoing diagnostic learning and proficiency testing in urological surgical pathology to individual pathologists, trainees and laboratories. Participants can assess their diagnostic skills and compare performance with that of their peers with the purpose of performance improvement. Case selections include a variety of neoplastic and nonneoplastic entities.

Catalogue Number

13280102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Ten diagnostic challenges are provided as whole slide H&E images, and ancillary testing if relevant, in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

Urological Histopathology

Additional Comments

Learning objective: Upon completion of this activity, participants will have an enhanced understanding of urological pathology and will be able to identify gaps in their diagnostic skills. The planners and others involved in control of content for this program have declared no relevant financial relationships with ineligible companies.

Product details last updated on August 20, 2025