Anatomical Pathology Archives - Page 2 of 3

HER2 Brightfield ISH (BRISH) Breast Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in breast cancer

Catalogue Number

13320102

Frequency (No of surveys/year)

2

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH (single or dual probe) slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March, August

Measurand/Test

Single probe of Dual probe HER2 BRISH for breast cancer interpretation

Product details last updated on August 20, 2020

HER2 Brightfield ISH (BRISH) Breast Technical

Proficiency testing for laboratories performing HER2 BRISH staining on breast cases

Catalogue Number

13250102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block are to be stained for HER2 BRISH

Schedule

August

Measurand/Test

HER2 BRISH breast

Storage and Handling

Room temperature

Product details last updated on August 20, 2020

HER2 Brightfield ISH (BRISH) Gastric Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in gastric cases.

Catalogue Number

13130102

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

HER2 BRISH for gastric cancer interpretation

Product details last updated on August 20, 2020

HER2 Brightfield ISH (BRISH) Gastric Technical

Proficiency testing for laboratories performing HER2 BRISH staining on gastric cases.

Catalogue Number

13260102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block are to be stained for HER2 BRISH.

Schedule

August

Measurand/Test

HER2 BRISH Gastric

Storage and Handling

Room temperature

Product details last updated on August 20, 2020

Immunohistochemistry Breast Markers

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13150102

Frequency (No of surveys/year)

1

Cases/samples per survey

5

Sample Type

Unstained formalin fixed paraffin sections comprising of 5 breast cancer cases in a composite tissue block to be stained for ER, PR, HER2 and 2 additional antibodies.

Schedule

August

Measurand/Test

ER, PR, HER2, CK 5/6, Ki67. Additional option of PD-L1 for TNBC.

Storage and Handling

Room temperature

Additional Comments

PD-L1 for TNBC interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.

Product details last updated on August 20, 2020

Immunohistochemistry Breast Markers Audit

Quality assurance activity for laboratories reporting immunohistochemistry (IHC) and in-situ hybridization (ISH) breast markers through an audit of clinical results. There is no technical component to this survey, but it comprises online submission of the hormone receptor and HER2 status for each case of early invasive primary (not stage 4 disease) breast carcinoma.

Catalogue Number

13160102

Frequency (No of surveys/year)

1

Cases/samples per survey

100

Sample Type

A maximum of 100 cases from the preceding year are submitted.

Schedule

February

Measurand/Test

Breast marker audit of cases reported by participant

Product details last updated on July 31, 2020

Immunohistochemistry General

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13170102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 general markers

Schedule

February

Measurand/Test

CD56 (alternate synaptophysin), MSH6, HMB45 (alternate MelanA)

Storage and Handling

Room temperature

Product details last updated on August 19, 2020

Immunohistochemistry Lymphoma Markers

Proficiency testing for laboratories processing immunohistochemistry. A variety of lymphoma markers are assessed.

Catalogue Number

13180102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 lymphoma markers.

Schedule

February

Measurand/Test

CD4 (alternate CD8), CD43 (alternate CD5), BOB-1 (alternate Bcl-2)

Storage and Handling

Room temperature

Product details last updated on August 19, 2020

Immunohistochemistry PD-L1 for non-small cell lung carcinoma (UKNEQAS)

In collaboration with UK NEQAS. Proficiency testing for laboratories processing PD-L1 immunohistochemistry for non-small cell lung carcinoma. This is a technical proficiency testing module only.

Catalogue Number

13270102

Frequency (No of surveys/year)

4

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue and cell lines block to be stained for PD-L1

Schedule

May, August, November, February

Measurand/Test

PD-L1 for non-small cell lung carcinoma

Storage and Handling

Room temperature

Additional Comments

PD-L1 interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.

Product details last updated on August 19, 2020

Mohs Diagnostic

Proficiency testing for dermatopathology Mohs Fellows and trainees.

Catalogue Number

13190102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal.

Schedule

March

Measurand/Test

Mohs surgery histopathology

Product details last updated on July 31, 2020

Neuropathology Diagnostic

Proficiency testing for laboratories and pathologists reporting neuropathology. Educational resource for other laboratories and trainees.

Catalogue Number

13200102

Frequency (No of surveys/year)

1

Cases/samples per survey

12

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Neuropathology

Product details last updated on August 20, 2020

Neuropathology Immunohistochemistry and Technical

Proficiency testing for laboratories processing neuropathology specimens.

Catalogue Number

13140102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

This is a combined module where unstained formalin fixed paraffin sections are provided for immunohistochemical and special staining.

Schedule

April

Measurand/Test

Myelin and BRAF V600E (alternate Neurofilament protein)

Storage and Handling

Room temperature

Product details last updated on August 20, 2020