Anatomical Pathology Archives - Page 2 of 4

Gynaecology Diagnostic

Proficiency testing for laboratories and pathologists reporting gynaecological pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13110102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Gynaecological Pathology

Product details last updated on August 20, 2020

Haematopathology Diagnostic

Proficiency testing for laboratories and pathologists reporting haematopathology. Educational resource for other laboratories and trainees.

Catalogue Number

13290101

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Haematopathology Histopathology

Product details last updated on August 31, 2023

HER2 Brightfield ISH (BRISH) Breast Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in breast cancer

Catalogue Number

13320101

Frequency (No of surveys/year)

2

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March, August

Measurand/Test

Dual probe HER2 BRISH for breast cancer interpretation. Single probe will no longer be offered in 2023.

Product details last updated on February 14, 2023

HER2 Brightfield ISH (BRISH) Breast Technical

Proficiency testing for laboratories performing brightfield in situ hybridisation. HER2 for breast and gastric cases will be offered annually. Additional ISH programs will be rotated on an annual basis. In 2024 the additional module offered is Lambda Light Chain in situ hybridisation.

Catalogue Number

13250102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Breast

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 31, 2023

HER2 Brightfield ISH (BRISH) Gastric Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in gastric cases.

Catalogue Number

13130101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

HER2 BRISH for gastric cancer interpretation

Product details last updated on September 18, 2023

HER2 Brightfield ISH (BRISH) Gastric Technical

Proficiency testing for laboratories performing brightfield in situ hybridisation. HER2 for breast and gastric cases will be offered annually. Additional ISH programs will be rotated on an annual basis. In 2024 the additional module offered is Lambda Light Chain in situ hybridisation.

Catalogue Number

13260102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Gastric

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 31, 2023

Immunohistochemistry Breast Markers

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13150102

Frequency (No of surveys/year)

1

Cases/samples per survey

5

Sample Type

Unstained formalin fixed paraffin sections comprising of 5 breast cancer cases in a composite tissue block to be stained for ER, PR, HER2 and 2 additional antibodies.

Schedule

August

Measurand/Test

ER, PR, HER2 IHC, p40, e-Cadherin

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

PD-L1 for TNBC interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.

Product details last updated on August 31, 2023

Immunohistochemistry Breast Markers Audit

Quality assurance activity for laboratories reporting immunohistochemistry (IHC) and in-situ hybridization (ISH) breast markers through an audit of clinical results. There is no technical component to this survey, but it comprises online submission of the hormone receptor and HER2 status for each case of early invasive primary (not stage 4 disease) breast carcinoma. 50-100 samples are required for assessment. Laboratories providing less than 50 samples will not qualify for assessment.

Catalogue Number

13160102

Frequency (No of surveys/year)

1

Cases/samples per survey

100

Sample Type

A maximum of 100 cases from the preceding year are submitted.

Schedule

February

Measurand/Test

Breast marker audit of cases reported by participant

Product details last updated on August 3, 2021

Immunohistochemistry General

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13170102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 general markers

Schedule

February

Measurand/Test

BRAF (alternate SOX10); OCT (3/4) (alternate CD117); INSM1 (alternate S100)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 31, 2023

Immunohistochemistry Lymphoma Markers

Proficiency testing for laboratories processing immunohistochemistry. A variety of lymphoma markers are assessed.

Catalogue Number

13180102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 lymphoma markers.

Schedule

February

Measurand/Test

Stains tested in 2024: Cyclin D1 (alternate SOX11), MUM1 (alternate CD138), CD4 (alternate PD1)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 31, 2023

Immunohistochemistry Mismatch Repair (MMR) protein

Proficiency testing for laboratories processing immunohistochemistry. Two mismatch repair (MMR) proteins are assessed annually. Colorectal cases are assessed annually and non-colorectal cases are rotated annually.

Catalogue Number

13430102

Frequency (No of surveys/year)

1

Cases/samples per survey

4

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 2 MMR protein markers.

Schedule

May

Measurand/Test

MLH1 and PMS2 on colorectal carcinoma and a second tissue type

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on August 31, 2023

Immunohistochemistry PD-L1 for HNSCC

Proficiency testing for laboratories performing PD-L1 testing. This is a technical proficiency testing program only.

Catalogue Number

13460102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per module

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for HNSCC

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

PD-L1 interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.

Product details last updated on June 14, 2023