Anatomical Pathology

ALK Translocation for non-small cell lung carcinoma (NSCLC): FISH

Proficiency testing for laboratories staining ALK immunohistochemistry. Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13010102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK FISH

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on June 14, 2023

ALK Translocation for non-small cell lung carcinoma (NSCLC): IHC

Proficiency testing for laboratories staining ALK immunohistochemistry. Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13020102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK IHC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on June 14, 2023

ALK Translocation for non-small cell lung carcinoma (NSCLC): Molecular

Proficiency testing for laboratories staining ALK immunohistochemistry. Proficiency testing for laboratories interpreting ALK translocation.

Catalogue Number

13030102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Schedule

May

Measurand/Test

ALK Molecular

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on June 14, 2023

Breast Diagnostic

Proficiency testing for laboratories and pathologists reporting breast pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13040102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Breast Histopathology

Product details last updated on August 20, 2020

Dermatopathology Diagnostic

Proficiency testing for laboratories and pathologists reporting dermatopathology. Educational resource for other laboratories/trainees.

Catalogue Number

13050102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Skin Histopathology

Product details last updated on July 31, 2020

Electron Microscopy Diagnostic

Proficiency testing for laboratories and pathologists reporting transmission electron microscopy. Educational resource for other laboratories/trainees.

Catalogue Number

13060102

Frequency (No of surveys/year)

1

Cases/samples per survey

3 (educational case may be included)

Schedule

September

Measurand/Test

Transmission Electron Microscopy

Product details last updated on August 11, 2022

Electron Microscopy Technical

Proficiency testing for laboratories processing transmission electron microscopy specimens.

Catalogue Number

13070102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Submission of Electron Micrographs prepared by the laboratory. Laboratory practice questionnaire.

Schedule

September

Measurand/Test

Transmission Electron Microscopy techniques

Product details last updated on August 11, 2022

Fluorescence in-situ Hybridisation (FISH) Diagnostic

Proficiency testing for laboratories reporting solid tumour fluorescence in-situ hybridisation. A different probe is tested each year (CCND1/CCND2 in 2025).

Catalogue Number

13310102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections to be stained and interpreted for 1p/19q FISH probe.

Schedule

April

Measurand/Test

CCND1/CCND2

Product details last updated on July 29, 2024

Forensic Diagnostic

Proficiency testing for laboratories and pathologists reporting forensic pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13080102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Forensic Pathology

Product details last updated on July 31, 2020

Gastrointestinal Diagnostic

Proficiency testing for laboratories and pathologists reporting gastrointestinal pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13090102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Gastrointestinal Histopathology

Product details last updated on August 20, 2020

General Diagnostic

Proficiency testing for laboratories and pathologists reporting routine Anatomical Pathology. Educational resource for trainees.

Catalogue Number

13100102

Frequency (No of surveys/year)

3

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

February, May, September

Measurand/Test

General Histopathology

Product details last updated on August 20, 2020

Gynaecology Diagnostic

Proficiency testing for laboratories and pathologists reporting gynaecological pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13110102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Gynaecological Pathology

Product details last updated on August 20, 2020

Head and Neck Diagnostic

Proficiency testing for laboratories and pathologists reporting head and neck pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13300102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Head and Neck Histopathology

Product details last updated on July 29, 2024

HER2 Brightfield ISH (BRISH) Breast Diagnostic

Proficiency testing for individual pathologists involved in the diagnostic interpretation of results for HER2 BRISH testing in breast cases.

Catalogue Number

13320101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Dual probe HER2 BRISH for breast cancer interpretation.

Product details last updated on July 29, 2024

HER2 Brightfield ISH (BRISH) Breast Technical

Proficiency testing for laboratories performing HER2 brightfield in situ hybridisation in breast cases.

Catalogue Number

13250102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Breast

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

HER2 Brightfield ISH (BRISH) Gastric Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in gastric cases.

Catalogue Number

13130101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections of H&E, HER2 IHC and HER2 BRISH slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

HER2 BRISH for gastric cancer interpretation

Product details last updated on July 29, 2024

HER2 Brightfield ISH (BRISH) Gastric Technical

Proficiency testing for laboratories performing HER2 brightfield in situ hybridisation in gastric cases.

Catalogue Number

13260102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

HER2 BRISH Gastric

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry Breast Markers

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13150102

Frequency (No of surveys/year)

1

Cases/samples per survey

5

Sample Type

Unstained formalin fixed paraffin sections comprising of 5 breast cancer cases in a composite tissue block to be stained for ER, PR, HER2 and 2 additional antibodies.

Schedule

August

Measurand/Test

ER, PR, HER2 IHC, SMMS-1, CK5/6

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

PD-L1 for TNBC interpretation proficiency testing is offered free of charge to RCPAQAP participants through IQNPath. The anatomical pathology team can be contacted for further details.


Product details last updated on July 29, 2024

Immunohistochemistry Breast Markers Audit

Quality assurance activity for laboratories reporting immunohistochemistry (IHC) and in-situ hybridization (ISH) breast markers through an audit of clinical results. There is no technical component to this survey, but it comprises online submission of the hormone receptor and HER2 status for each case of early invasive primary (not stage 4 disease) breast carcinoma. 50-100 samples are required for assessment. Laboratories providing less than 50 samples will not qualify for assessment.

Catalogue Number

13160102

Frequency (No of surveys/year)

1

Cases/samples per survey

100

Sample Type

A maximum of 100 cases from the preceding year are submitted.

Schedule

February

Measurand/Test

Breast marker audit of cases reported by participant

Product details last updated on August 3, 2021

Immunohistochemistry General

Proficiency testing for laboratories processing immunohistochemistry.

Catalogue Number

13170102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 general markers

Schedule

February

Measurand/Test

PRAME (MelanA); Claudin4 (BAP1); PIN4 (P63)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry HER2-low scoring in Breast Cancer

Proficiency testing for individual pathologists who are scoring HER2 IHC in breast cancer

What's new

New for 2025

Catalogue Number

13550101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs cannot be purchased for this program.

Schedule

July

Measurand/Test

HER2 IHC readout

Product details last updated on July 29, 2024

Immunohistochemistry Lymphoma Markers

Proficiency testing for laboratories processing immunohistochemistry. A variety of lymphoma markers are assessed.

Catalogue Number

13180102

Frequency (No of surveys/year)

1

Cases/samples per survey

3

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 3 lymphoma markers.

Schedule

February

Measurand/Test

CD3 (Bcl2); C-Myc (CD45); Ki-67 (CD20)

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry Mismatch Repair (MMR) protein

Proficiency testing for laboratories processing immunohistochemistry. Two mismatch repair (MMR) proteins are assessed annually. Colorectal cases are assessed annually and non-colorectal cases are rotated annually.

Catalogue Number

13430102

Frequency (No of surveys/year)

1

Cases/samples per survey

4

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained for 2 MMR protein markers.

Schedule

May

Measurand/Test

MSH2 and MSH6 on colorectal carcinoma and a second tissue type

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry PD-L1 for HNSCC

Proficiency testing for laboratories performing PD-L1 testing. This is a technical proficiency testing program only.

Catalogue Number

13460102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for HNSCC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry PD-L1 for NSCLC

Proficiency testing for laboratories performing PD-L1 testing. This is a technical proficiency testing program only.

For pathologist scoring proficiency testing, please see the new program “Immunohistochemistry PD-L1 scoring in NSCLC (TPS)”

Catalogue Number

13440102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for NSCLC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry PD-L1 for TNBC

Proficiency testing for laboratories performing PD-L1 testing. This is a technical proficiency testing program only.

Catalogue Number

13450102

Frequency (No of surveys/year)

2

Cases/samples per survey

Varies per survey

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be stained for PD-L1

Schedule

February, August

Measurand/Test

PD-L1 for TNBC

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Immunohistochemistry PD-L1 scoring in NSCLC (TPS)

Proficiency testing for individual pathologists who are applying a Tumour Proportion Score (TPS) to PD-L1 IHC in NSCLC

For laboratory technical proficiency testing, please refer to program “Immunohistochemistry PD-L1 for NSCLC

What's new

New for 2025

Catalogue Number

13560101

Frequency (No of surveys/year)

1

Cases/samples per survey

6

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs cannot be purchased for this program.

Schedule

August

Measurand/Test

PD-L1 in NSCLC TPS readout

Product details last updated on July 29, 2024

Kappa Light Chain in situ hybridisation

Proficiency testing for laboratories performing kappa light chain in situ hybridisation.

Catalogue Number

13410102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block.

Schedule

May

Measurand/Test

Kappa ISH

Product details last updated on July 29, 2024

Mohs Diagnostic

Proficiency testing for dermatopathology Mohs Fellows and trainees.

Catalogue Number

13190102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal.

Schedule

March

Measurand/Test

Mohs surgery histopathology

Product details last updated on July 31, 2020

Neuropathology Diagnostic

Proficiency testing for laboratories and pathologists reporting neuropathology. Educational resource for other laboratories and trainees.

Catalogue Number

13200102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

April

Measurand/Test

Neuropathology

Product details last updated on August 3, 2021

Neuropathology Immunohistochemistry and Technical

Proficiency testing for laboratories processing neuropathology specimens.

Catalogue Number

13140102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

This is a combined module where unstained formalin fixed paraffin sections are provided for immunohistochemical and special staining.

Schedule

May

Measurand/Test

ATRX and Myelin stain

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Oral and Maxillofacial Diagnostic

Proficiency testing for laboratories and pathologists reporting oral and maxillofacial histopathology. Educational resource for other laboratories and trainees.

Catalogue Number

13210102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

March

Measurand/Test

Oral and Maxillofacial Histopathology

Product details last updated on August 20, 2020

Paediatric Diagnostic

Proficiency testing for laboratories and pathologists reporting paediatric and perinatal pathology. Educational resource for other laboratories and trainees.

Catalogue Number

13220102

Frequency (No of surveys/year)

1

Cases/samples per survey

12

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Paediatric Histopathology, Perinatal Histopathology

Product details last updated on November 20, 2023

Renal Medical Diagnostic

Proficiency testing for laboratories and pathologists reporting medical renal pathology. Educational resource for other laboratories/trainees.

Catalogue Number

13470102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

July

Measurand/Test

Medical Renal Histopathology

Product details last updated on July 29, 2024

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): FISH

Proficiency testing for laboratories staining ROS1 immunohistochemistry. Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13360102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 FISH

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.


Product details last updated on August 31, 2023

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): IHC

Proficiency testing for laboratories staining ROS1 immunohistochemistry. Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13370102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 IHC

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.


Product details last updated on August 31, 2023

ROS1 Translocation for non-small cell lung carcinoma (NSCLC): Molecular

Proficiency testing for laboratories staining ROS1 immunohistochemistry. Proficiency testing for laboratories interpreting ROS1 translocation.

Catalogue Number

13380102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ROS1.

Schedule

May

Measurand/Test

ROS1 Molecular

Storage and Handling

Upon receipt, store samples at room temperature

Additional Comments

In conjunction with the RCPAQAP Molecular Genetics Discipline, this program consists of the following selectable modules: Immunohistochemistry ROS1 staining for technical and interpretation proficiency; ROS1 FISH interpretation proficiency and ROS1 Molecular techniques interpretation proficiency.


Product details last updated on August 31, 2023

Sarcoma Gene Testing – FISH

Proficiency testing for laboratories performing and reporting sarcoma gene testing from FFPE tissue. Two genes are assessed annually.

Catalogue Number

13480102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

ALK and CIC-DUX4

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Sarcoma Gene Testing – IHC

Proficiency testing for laboratories performing and reporting sarcoma gene testing from FFPE tissue. Two genes are assessed annually.

Catalogue Number

13500102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

ALK and CIC-DUX4

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Sarcoma Gene Testing – Molecular

Proficiency testing for laboratories performing and reporting sarcoma gene testing from FFPE tissue. Two genes are assessed annually.

Catalogue Number

13510102

Frequency (No of surveys/year)

1

Cases/samples per survey

2

Sample Type

Unstained formalin fixed paraffin sections comprising of composite tissue blocks to be processed and reported using the laboratory's preferred method.

Schedule

March

Measurand/Test

ALK and CIC-DUX4

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Technical Frozen Section

Proficiency testing for histopathology laboratories performing the frozen section procedure.

Catalogue Number

13230102

Frequency (No of surveys/year)

1

Cases/samples per survey

1

Sample Type

Participants submit a stained and coverslipped section on a glass slide for assessment of block/section preparation and staining.

Schedule

February

Measurand/Test

Frozen section

Product details last updated on May 22, 2023

Technical General

Proficiency testing for laboratories performing general histopathology processes.

Catalogue Number

13240102

Frequency (No of surveys/year)

2

Cases/samples per survey

1-2

Sample Type

Unstained formalin fixed paraffin sections are provided for most exercises. Unstained tissue sections are submitted by participants for the Processing and Sectioning exercise

Schedule

February, August

Measurand/Test

H&E, Processing and Sectioning, Iron special stain, Mucicarmine special stain, Digital Pathology and Artificial Intelligence laboratory practice questionnaire.

Storage and Handling

Upon receipt, store samples at room temperature

Product details last updated on July 29, 2024

Urology Diagnostic

Proficiency testing for laboratories and pathologists reporting urological pathology. Educational resource for other laboratories and trainees.

Catalogue Number

13280102

Frequency (No of surveys/year)

1

Cases/samples per survey

10

Sample Type

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Schedule

August

Measurand/Test

Urological Histopathology

Product details last updated on August 19, 2020