Anatomical Pathology

Anatomical Pathology is the branch of pathology that deals with the tissue diagnosis of disease. The RCPAQAP Anatomical Pathology discipline offers diagnostic proficiency testing programs for histopathologists. Diagnostic modules include the flagship General Diagnostic Module covering a variety of specimen types and a selection of other speciality modules. The diagnostic programs can also be used as an educational resource. The RCPAQAP Anatomical Pathology discipline also offers general and speciality immunohistochemistry and technical proficiency testing programs for histology laboratories.

ALK Translocation for non-small cell lung carcinoma (NSCLC)

Proficiency testing for laboratories staining ALK immunohistochemistry. Proficiency testing for laboratories interpreting ALK translocation.

Formally part of the RCPAQAP Molecular Genetics Discipline, the ‘ALK Translocation for NSCLC’ program has been combined with the RCPAQAP Anatomical Pathology ‘Immunohistochemistry for Lung Markers’ program. This program now consists of the following selectable modules: Immunohistochemistry ALK staining for technical and interpretation proficiency; ALK FISH interpretation proficiency and ALK Molecular techniques interpretation proficiency, Participants select the module/s appropriate for ALK translocation testing within their laboratory.

Unstained formalin fixed paraffin sections comprising of composite tissue block to be stained/processed/interpreted for ALK.

Frequency / Number of samples

1 survey per year / 1 exercise per survey

Tests

ALK IHC, ALK FISH, ALK Molecular

Product details last updated on July 29, 2019

Bone and Soft Tissue Diagnostic

Two subspecialties will be showcased each year over a 3–4 year period and will be convened by a guest pathologist. In 2020, these subspecialties will be Bone and Soft Tissue and Endocrine Pathology. Modules suggested for future years include Head & Neck.

Proficiency testing for laboratories and pathologists reporting bone and soft tissue pathology. Educational resource for other laboratories and trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey in 2020 / 10 cases per survey (will not recure in 2021)

Tests

Bone and Soft Tissue Histopathology

Product details last updated on July 29, 2019

Breast Diagnostic

Proficiency testing for laboratories and pathologists reporting breast pathology. Educational resource for trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey per year / 10 cases per survey

Tests

Breast Histopathology

Product details last updated on July 29, 2019

Dermatopathology Diagnostic

Proficiency testing for laboratories and pathologists reporting dermatopathology. Educational resource for trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey per year / 10 cases per survey

Tests

Skin Histopathology

Product details last updated on July 29, 2019

Electron Microscopy Diagnostic

Proficiency testing for laboratories and pathologists reporting transmission electron microscopy. Electron micrographs are available in the myQAP portal. USBs can be purchased separately

Frequency / Number of samples

1 survey per year / 3 cases per survey (additional educational case may be included)

Tests

Transmission Electron Microscopy

Product details last updated on July 29, 2019

Endocrine Diagnostic

Two subspecialties will be showcased each year over a 3–4 year period and will be convened by a guest pathologist. In 2020, these subspecialties will be Bone & Soft Tissue and Endocrine Pathology. Modules suggested for future years include Head & Neck.

Proficiency testing for laboratories and pathologists reporting endocrine pathology. Educational resource for other laboratories and trainees.

Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey in 2020 / 10 cases per survey (will not recur in 2021)

Tests

Endocrine Histopathology

Product details last updated on July 29, 2019

Fluorescence in-situ Hybridisation (FISH) Diagnostic

Proficiency testing for laboratories reporting fluorescence in-situ hybridisation. A different probe to be tested each year (BCL2 in 2020).
Unstained formalin fixed paraffin sections to be stained and interpreted for BCL2 FISH probe. Virtual H&E and BCL2 immunohistochemistry will also be available to assist with interpretation. Participants requiring ALK FISH diagnostic testing are requested to enrol in the ALK Translocation for non-small cell lung carcinoma (NSCLC) program.

Frequency / Number of samples

1 survey per year / 1 exercise per survey

Tests

BCL2, FISH

Product details last updated on August 29, 2019

Forensic Diagnostic

Proficiency testing for laboratories and pathologists reporting forensic pathology. Educational resource for routine laboratories and trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey per year / 10 cases per survey

Tests

Forensic Pathology

Product details last updated on July 29, 2019

Gastrointestinal Diagnostic

Proficiency testing for laboratories and pathologists reporting gastrointestinal pathology. Educational resource for other laboratories and trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey per year / 10 cases per survey

Tests

Gastrointestinal Pathology

Product details last updated on July 29, 2019

General Diagnostic

Proficiency testing for laboratories and pathologists reporting routine anatomical pathology. Educational resource for trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

3 surveys per year / 10 cases per survey (total of 30 cases)

Tests

General Diagnostic Histopathology

Product details last updated on July 29, 2019

Gynaecological Diagnostic

Proficiency testing for laboratories and pathologists reporting gynaecological pathology. Educational resource for other laboratories and trainees. Stained sections are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

Frequency / Number of samples

1 survey per year / 10 cases per survey

Tests

Gynaecological Histopathology

Product details last updated on July 29, 2019

HER2 BRISH Breast Diagnostic

Proficiency testing for individual pathologists who are involved in the diagnostic interpretation of results for HER2 BRISH testing in breast cancer. Stained sections of H&E, HER2 IHC and HER2 BRISH (single or dual probe) slides are provided as virtual microscope slide images in the myQAP portal. USBs can be purchased separately.

As this is available as an individual enrolment only, laboratories will be capped for invoicing purposes at 5 enrolments.

Frequency / Number of samples

2 surveys per year / 6 cases per survey

Tests

Single probe or Dual probe HER2 BRISH for breast cancer interpretation

Product details last updated on July 29, 2019