Serology
Serology is the study of the blood (specifically serum) and other bodily fluids, for the identification of immunological response, essentially antibodies, to an infectious agent. Serological tests can be used for the diagnosis and monitoring of a range of infectious viral, bacterial, fungal and parasitic diseases and are of particular importance in pregnancy and the immunodeficient. The RCPAQAP has a comprehensive range of EQA programs covering a variety of diagnostic tests used in infectious serological screening, surveillance and immunity evaluation.
Antenatal – Rubella serology
Clinical material (Liquid Serum / Plasma – 0.7 mL) provided to assess the detection of Rubella using serological markers
Frequency / Number of samples
4 surveys / 2 samples per survey
Tests
Rubella Total Antibody, Rubella IgG, Rubella IgM, Rubella Avidity, Rubella Interpretation
Antenatal – Syphilis serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of Syphilis using serological markers
Frequency / Number of samples
4 surveys / 2 samples per survey
Tests
Syphilis Total Antibody, Syphilis RPR, Syphilis Agglutination (TPHA/TPPA), Syphilis FTA-ab, Syphilis VDRL, Syphilis ICT, Syphilis IgG, Syphilis IgM, Syphilis Immunoblot, Syphilis Interpretation
Bacterial – Brucella serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of various Brucella species using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Brucella abortus Agglutination, Brucella melitensis Agglutination, Brucella abortus/melitensis/bovis/suis grp Agglutination, Brucella Anti-human Globulin, Brucella IgG-IgM Differential, Brucella CFT, Brucella IgG, Brucella IgM, Brucella immunocapture-agglutination (ICA), Brucella Interpretation
Bacterial – Chlamydia genus serology
Clinical material provided (Liquid Serum / Plasma – 0.3 mL) to assess the detection of various Chlamydia species using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Chlamydia pneumoniae IgG, Chlamydia pneumoniae IgG IFA, Chlamydia pneumoniae IgM, Chlamydia pneumoniae IgA, Chlamydia pneumoniae Total Antibody, Chlamydia genus IgG, Chlamydia genus IgG IFA, Chlamydia genus IgM, Chlamydia genus IgA, Chlamydia genus Total Antibody, Chlamydia psittaci IgG, Chlamydia psittaci IgM, Chlamydia psittaci IgA, Chlamydia psittaci Total Antibody, Chlamydia trachomatis Antibody IgG, Chlamydia trachomatis Antibody IgG IFA, Chlamydia trachomatis Antibody IgA, Chlamydia trachomatis Antibody IgM, Chlamydia trachomatis Total Antibody, Chlamydia Intepretation
Bacterial – Chlamydia trachomatis Antigen EIA/IFA
Simulated clinical material provided (Liquid Urine & Culture material- 0.4 mL) to assess the detection of Chlamydia trachomatis antigen
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Chlamydia trachomatis EIA, Chlamydia trachomatis IFA/DFA, Chlamydia Intepretation
Bacterial – Helicobacter pylori serology
Clinical material provided (Liquid Serum / Plasma – 0.35 mL) to assess the detection of Helicobacter pylori using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Helicobacter pylori Total Antibody, Helicobacter pylori IgG, Helicobacter pylori IgA, Helicobacter pylori IgM, Helicobacter pylori Interpretation
Bacterial – Legionella serology
Clinical material provided various Legionella species using serological markers (Liquid Serum – 0.3 mL) to assess the detection of
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Legionella CFT, Legionella IFA IgG, Legionella IFA IgM, Legionella IFA Total Antibody, Legionella IFA Pools, Legionella EIA IgM L.longbeachae, Legionella EIA IgM L.pneumophila, Legionella EIA IgG, Legionella EIA Total Antibody, Legionella Interpretation
Bacterial – Legionella Urinary Antigen
Clinical material provided (Liquid Urine – 1.0 mL) to assess the detection of Legionella urinary antigen
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Legionella Urinary Antigen Detection EIA, Legionella Urinary Antigen Detection ICT, Legionella Interpretation
Bacterial – Mycoplasma serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of Mycoplasma pneumoniae using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Mycoplasma IgA, Mycoplasma IgG, Mycoplasma IgM, Mycoplasma Total Antibody, Mycoplasma Interpretation
Bacterial – QuantiFERON – TB
Material provided (Lyophilised Serum / Plasma) to assess the detection of QuantiFERON® TB
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
QuantiFERON® TB (detection only)
Bacterial – Rickettsial serology
Clinical material provided (Liquid Serum / Plasma – 0.4 mL) to assess the detection of various Rickettsial species using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Spotted Fever Group Total Antibody, Spotted Fever Group IgG, Spotted Fever Group IgM, Rickettsia australis Total Antibody, Rickettsia australis IgG, Rickettsia australis IgM, Rickettsia conorii Total Antibody, Rickettsia conorii IgG, Rickettsia conorii IgM, Rickettsia rickettsii Total Antibody, Rickettsia rickettsii IgG, Rickettsia rickettsii IgM, Typhus Group Total Antibody, Typhus Group IgG, Typhus Group IgM, Rickettsia prowazekii Total Antibody, Rickettsia prowazekii IgG, Rickettsia prowazekii IgM, Rickettsia typhi Total Antibody, Rickettsia typhi IgG, Rickettsia typhi IgM, Scrub Typhus Group Total Antibody, Scrub Typhus Group IgG, Scrub Typhus Group IgM, Orientia tsutsugamushi IgG, Orientia tsutsugamushi IgM, Rickettsia Interpretation
Bacterial – Streptococcal serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of Group A Streptococcal using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Streptococcus ASOT, Streptococcus Streptozyme, Streptococcus Anti-DNase B, Streptococcus Antistreptokinase, Streptococcus Interpretation
