Serology
Serology is the study of the blood (specifically serum) and other bodily fluids, for the identification of immunological response, essentially antibodies, to an infectious agent. Serological tests can be used for the diagnosis and monitoring of a range of infectious viral, bacterial, fungal and parasitic diseases and are of particular importance in pregnancy and the immunodeficient. The RCPAQAP has a comprehensive range of EQA programs covering a variety of diagnostic tests used in infectious serological screening, surveillance and immunity evaluation.
Alphavirus serology
Clinical material provided (Liquid Serum / Plasma – 0.4 mL) to assess the detection of various Alphaviruses using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Alphavirus IgG; IgM
Barmah Forest Virus IgG; IgM; Total Antibody
Chikungunya Virus IgG; IgM; Total Antibody
Ross River Virus IgG; IgM; Total Antibody
Sindbis Virus IgG; IgM; Total Antibody
Bordetella pertussis serology
Clinical material provided (Liquid Serum / Plasma – 0.25 mL) to assess the detection of Bordetella pertussis using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Bordetella pertussis IgA; IgG; IgM
Bordetella pertussis Toxin & FHA IgA; Toxin & FHA IgG
Toxin & FHA IgM
Bordetella pertussis Toxin IgA; Toxin IgG; Toxin IgM
Brucella serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of various Brucella species using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Brucella abortus Agglutination; Brucella melitensis Agglutination; Brucella abortus/melitensis/bovis/suis grp Agglutination; Brucella Anti-human Globulin; Brucella IgG-IgM Differential; Brucella CFT; Brucella IgG; Brucella IgM; Brucella immunocapture-agglutination (ICA)
Chlamydia genus serology
Clinical material provided (Liquid Serum / Plasma – 0.3 mL) to assess the detection of various Chlamydia species using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Chlamydia genus IgA; IgG; IgM; Total Antibody
Chlamydia pneumoniae IgA; IgG; IgM; Total Antibody
Chlamydia psittaci IgA; IgG; IgM; Total Antibody
Chlamydia trachomatis Antibody IgA; IgG; IgM; Total Antibody
Cryptococcal Antigen
Clinical or culture material provided (Liquid Serum or culture supernatant – 0.5 mL) to assess the detection of Cryptococcal Antigen
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Cryptococcus Antigen Detection
Cytomegalovirus serology
Clinical material provided (Liquid Serum / Plasma – 0.6 mL) to assess the detection of Cytomegalovirus using serological markers
Frequency / Number of samples
4 surveys / 2 samples per survey
Tests
Cytomegalovirus Avidity; IgG; IgM; Total Antibody
Dengue Virus serology
Clinical material provided (Liquid Serum / Plasma – 0.4 mL) to assess the detection of Dengue virus ONLY using serological markers.
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Dengue IgG: Sero-prevalence; Capture
Dengue Virus IgM;
Dengue Virus NS1 Antigen
Dengue Virus ICT NS1/IgG/IgM
Entamoeba serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of Entamoeba using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Entamoeba (CIEP, EIA IHA & IFA)
Epstein Barr Virus serology
Clinical material provided (Liquid Serum / Plasma – 0.6 mL) to assess the detection of Epstein Barr Virus using serological markers
Frequency / Number of samples
4 surveys / 2 samples per survey
Tests
EBV Avidity; EBV EA and EBNA IgA; EBV EA IgA; EBV EA IgG; EBV EBNA IgG; EBV EBNA IgM; EBV VCA IgA; EBV VCA IgG; EBV VCA IgM; Heterophile Antibody
Flavivirus serology
Clinical material provided (Liquid Serum / Plasma – 0.4 mL) to assess the detection of various Flaviviruses using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Dengue IgG: Sero-prevalence; Capture
Dengue Virus IgM; Total Antibody
Dengue Virus NS1 Antigen
Dengue Virus ICT NS1/IgG/IgM
Flavivirus IgG; IgM; Total Antibody
Japanese Encephalitis Virus IgG; IgM; Virus Total Antibody
Kokobera Virus IgG; IgM; Total Antibody
Kunjin (West Nile) Virus IgG; IgM; Total Antibody
Murray Valley Encephalitis Virus IgG; IgM; Total Antibody
Yellow Fever IgG; IgM; Total Antibody
Zika Virus IgG; IgM; Total Antibody
Helicobacter pylori serology
Clinical material provided (Liquid Serum / Plasma – 0.35 mL) to assess the detection of Helicobacter pylori using serological markers
Frequency / Number of samples
2 surveys / 2 samples per survey
Tests
Helicobacter pylori IgA; IgG; IgM; Total Antibody
Hepatitis A serology
Clinical material provided (Liquid Serum / Plasma – 0.5 mL) to assess the detection of Hepatitis A using serological markers
Frequency / Number of samples
6 surveys / 2 samples per survey
Tests
Anti-HAV IgG; Anti-HAV IgM; Anti-HAV Total Antibody
